Clinical Trials

Since our beginning, we have been on the cutting edge of advances in treating some very common eye conditions. We have been involved in clinical trials that have led to approval of three major treatments for wet age-related macular degeneration, and we are now enrolling or will soon begin to enroll patients in three more studies.

Below is a list of all the studies which Retina Specialists are participating or have participated at Retina Specialists. Please call our office at 410-296-9748 for more information.


Current Studies

Age-related Macular Degeneration (Wet - Neovascularization)

LUCERNE/Roche Phase III Follow-Up
ARCHWAY/Roche Phase III Follow-Up
PORTAL/Roche Open Label Ext. Follow Up

Age Related Macular Degeneration (Dry-Geographic Atrophy)

ISIS 696844-CS5/Ionis Phase II RECRUITING
Derby/Apellis Phase III Recruitment Closed

Diabetic Macular Edema

Rhine/Roche Phase III Follow Up
Pagoda/Roche Phase III RECRUITING

Diabetic Retinopathy

Pavilion/Roche Phase III Upcoming

PREVIOUS CLINICAL TRIALS:

Macular Degeneration (Wet)

LADDER/Roche Phase II
Cedar/Allergan Phase III
OPT-302-1002/Opthea Phase IIb
CAPELLA/Regeneron Phase II
MAKO/Ohr Phase III
SOLARIS/Ophthotech Phase III
NEXUS/Lpath Phase II
CATT Follow-up/ National Eye Institute Comparative Trial
VIEW-1 Extension/Regeneron Phase III
CATT/National Eye Institute Comparative Trial
COBALT/OPKO Phase III
LEVEL/OSI – EyeTech Phase IV
HORIZON/Genentech Open Label
SAILOR/Genentech Phase IIIb
ACUITY Phase I
CARE/Acuity Phase II
GENAERA 208/209 Phase II
GENAERA 301 Phase III
MARINA/Genentech Phase III
ANCHOR/Genentech Phase III

Macular Degeneration (Dry)

CLG561-2201/Alcon Proof of Concept
LAMPALIZUMAB/Genentech Phase III
OMASPECT/Genentech Extension Study
BAM114341/GlaxoSmithKline Phase II

Diabetic Retinopathy

MYL1701P-300/Mylan GmbH Biosimilar
PANORAMA/Regeneron Phase III
LUMINATE/Allegro Phase II
RISE/Genentech Phase III
DIAMOND/Macusight Phase II
PKC (MBDV)/Eli Lilly Open Label
PKC (MBCM)/Eli Lilly Phase III
RACE/Acuity Phase II

Nonclearing Vitreous Hemorrhage

Hyaluronidase/Advanced Corneal Phase III
Hyaluronidase/Advanced Corneal Phase II

Retinal Vein Occlusions

TOPAZ/Clearside Biomedical Phase III
COPERNICUS/Regeneron Phase III
VIBRANT/Regeneron Phase III
Posurdex Study/Allergan Phase III

Click on this link for more information, and please contact our clinical coordinators at 410-296-9748 if you are interested in learning more about the latest clinical studies.